Appio Claudio Vacations from $1,013

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Your Appio Claudio Vacation

From its history to its culture, there's a lot to like about Appio Claudio. Book an Appio Claudio vacation package and prepare to experience the best of this neighborhood. When it's time to head out and explore, you'll find a lot of awesome attractions nearby including Ippodromo Capannelle, Anagnina Mall and La Romanina Shopping Center. Tick off one, two or all during your trip to Appio Claudio. Expedia can help turn your ideal Appio Claudio vacation into reality, whatever your budget or travel plans.

The Latest Appio Claudio Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Gregoriana

Hotel Gregoriana

Rome City Centre
$1,013
per person
Nov 2 - Nov 5
found 1 day ago
Roundtrip flight included
New York (NYC) to Rome (FCO)
9.4/10 Exceptional! (1,002 reviews)
Great hotel and location

Reviewed on Aug 18, 2026

JC Hotel

JC Hotel

Fonte Ostiense
Save 100% on your flight
$1,221
per person
Oct 25 - Oct 31
found 1 day ago
Roundtrip flight included
New York (NYC) to Rome (FCO)
8.2/10 Very Good! (135 reviews)
Hotiday Roma Trevi

Hotiday Roma Trevi

Rome City Centre
$2,010
per person
Oct 9 - Oct 15
found 1 day ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Rome (FCO)
No reviews
Hotel Delle Civette

Hotel Delle Civette

Nomentano
Save 100% on your flight
$1,451
per person
Sep 29 - Oct 4
found 1 day ago
Roundtrip flight included
Boston (BOS) to Rome (FCO)
9.6/10 Exceptional! (316 reviews)
Staff goes above and beyond to help guests. Every single aspect of the hotel was excellent. We plan to stay there again.

Reviewed on Aug 16, 2026

Hotel Splendide Royal - The Leading Hotels of the World

Hotel Splendide Royal - The Leading Hotels of the World

Rome City Centre
Save 100% on your flight
$3,552
per person
Oct 2 - Oct 8
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Rome (FCO)
9.4/10 Exceptional! (1,001 reviews)
5 star all around. Amazing property in heart of the city. Gorgeous room. They upgraded us to a corner suite. Tons of space. Beautiful linens furnishings and amenities. Staff incredibly helpful. Breakfast amazing. Rooftop terrace gorgeous. Good restaurant options around. Easy taxi grabs. Could not say enough good things about the Splendide.

Reviewed on Aug 18, 2026

Where to stay in Appio Claudio

Find the best Appio Claudio areas and neighborhoods for the activities you enjoy most. Learn more about Appio Claudio
A historic building with a dome and columns, surrounded by pedestrians and parked vehicles.

Rome City Centre

9 out of top 10 points of interest in this area

Follow in the footsteps of ancient Romans when you tour the Eternal City's most well-known historical sites and see where it started almost 3,000 years ago.

Find hotels in Rome City Centre
A classical fountain with multiple statues, including a prominent figure holding a staff, surrounded by water.

Rome Historic Centre

Enclosed by Aurelian Walls, this UNESCO-listed historic district boasts numerous museums, including the Capitoline Museums and Scuderie del Quirinale. Well-connected by public transport including the Roma Termini and Roma Ostiense stations which are nearby.

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The Colosseum with its arches and ruins, partially covered by vegetation.

Monti

Relax in wine bars and restaurants, take a walking tour and discover the famous Colosseum and other historic sites in one of Rome’s prominent districts.

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A cobblestone street with graffiti, a restaurant named 'CAGGIO', and people walking.

Trastevere

Narrow cobbled streets lined by ancient houses give this area a charming character. Enjoy lively pubs and restaurants at night, while being close to international academic institutions and the River Tiber.

Find hotels in Trastevere
A variety of cured meats and cheeses displayed in a market.

Trevi

Art galleries, churches, and museums are just a few things travelers like about Trevi. Sights like Trevi Fountain and Piazza di Trevi are spots to explore, and you can get around the greater Rome area at Barberini Station.

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Appio Claudio Hotel Deals

Hotel Quirinale

Hotel Quirinale

Via Nazionale 7 Rome RM
Fully refundableReserve now, pay when you stay
$157 nightly
$191 total
Aug 27 - Aug 28
Total with taxes and fees
8.8/10 Excellent! (1,932 reviews)
"Staff was very helpful and polite."

Reviewed on Aug 20, 2026

Hotel Quirinale
Hilton Rome Airport

Hilton Rome Airport

Via Arturo Ferrarin 2 Fiumicino RM
Fully refundableReserve now, pay when you stay
$244 nightly
$280 total
Aug 24 - Aug 25
Total with taxes and fees
8.4/10 Very Good! (3,331 reviews)
"Close to the airport"

Reviewed on Aug 21, 2026

Hilton Rome Airport
Massimi City Garden Hotel

Massimi City Garden Hotel

Largo Vincenzo Ambrosio, 9 Rome RM
Fully refundable
$83 nightly
$109 total
Aug 23 - Aug 24
Total with taxes and fees
9.4/10 Exceptional! (377 reviews)
"Hospitality great"

Reviewed on Aug 20, 2026

Massimi City Garden Hotel
See all 16,729 properties in Appio Claudio
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Stay near popular Appio Claudio attractions

Park of the Aqueducts

Park of the Aqueducts is just one of the places to see in Rome, so why not enjoy the other things to explore during your travels? Visit the notable monuments and churches in this vibrant area.
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Claudio Aqueduct

Learn about the local history of Rome when you spend time at Claudio Aqueduct.
See properties

Villa of the Quintilii

Learn about the local history of Rome when you take a trip to Villa of the Quintilii. Visit the churches and notable monuments in this vibrant area.
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Things to do

Rome Hop-On Hop-Off Big Bus Tour

Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus

$26
per adult
84% of travellers recommend
Rome Big Bus Hop-on, Hop-off Tour by Open-top Bus
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour

$79
per adult
84% of travellers recommend
Rome: Colosseum with Arena, Roman Forum and Palatine Guided Tour
Rome in a Day: Small Group Tour with Vatican, Colosseum & Historic Center

Rome in a Day: Small Group Tour with Vatican, Colosseum & Historic Center

$207
per adult
96% of travellers recommend
Rome in a Day: Small Group Tour with Vatican, Colosseum & Historic Center
See all activities in Rome
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.